Drug Discovery

New Avenues to Fight Serious Illness

菠菜网lol正规平台 researchers focus on new treatments for infectious diseases and bacterial infections, and ways to make existing therapies more effective. Studies also strive to better understand the underlying bases of human diseases, exploring the mechanisms that underlie breast cancer, chronic pain, Alzheimer’s and other dementias, schizophrenia, fetal alcohol syndrome, heart disease, and viral evolution. Below is a rotating selection of our standout investigators in these areas.

   ○ Recent News and Highlights
   ○ Related Strength: Biotechnology

• Selected Publications

  • 黄齐F.等。., (2020). β-Cell-specific ablation of sirtuin 4 does not affect nutrient-stimulated insulin secretion in mice. American Journal of 生理学 - Endocrinology and Metabolism, 319(4).

    Payumo,.等。., (2021). Adrenergic-Thyroid Horm一个 Interactions Drive Postnatal Thermogenesis and Loss of Mammalian Heart Regenerative Capacity. Circulation, 144(12).

    皮克特,米.等。., (2022). Separable mechanisms drive local and global polarity establishment in the Caenorhabditis elegans intestinal epithelium. Development, 149(22).

• Award Highlights

  • French, “The Role of Insulin Signaling in Developmental Ethanol Toxicity” — Department 健康的 & Human Services, 2020

    Radlauer, “Metallopolymers as Functional Metalloprotein Mimics with Secondary Coordination Sphere Interactions.” — 国家卫生研究院, NIGMS, 2020

    Radlauer, “LEAPS-MPS: Confinement of Organometallic Complexes within Structured Polymers for Site-Isolated Tandem Catalysis” — NSF, 2021

    Wang, "Elucidating the Mechanism for Allosteric Regulation of SIRT1 through the N-Terminal Region" — 国家卫生研究院, 2023

    Wang, “Intramolecular Allosteric Regulation of SIRT1 Deacetylase Activity by the N-terminal Domain” — 国家卫生研究院, 2019

    Paul, Visintainer, Pizarro, Wilkinson, “Transforming Undergraduate Teaching and Learning Through Culturally Sustaining, Active, and Asset-Based Approaches to Introductory 科学 Courses” — NSF, 2020

    Wilkinson, “Control of Muscle Proprioceptor Sensitivity” — NIGMS, 2018

• 创新

  • Baronated Nanoscale Sustate and Uses Thereof [pdf]
    Method for grafting boron shells onto diamond nanoparticles, enabling targeted boron neutron capture therapy for improved treatments.
    

    Nano Star Technology [pdf]
    New platform for targeted drug delivery and imaging.

• 子公司

  • CSUBIOTECH

    CSU STEM-​NET

Featured 教师

Rachael French
Department Chair of Biological 科学s
Drosophila, Ethanol, Development, Fetal Alcohol Effects, Behavior
ORCID: 0000-0001-9974-4293

弗兰克黄齐
Assistant Professor of Biological 科学s
生理学, Metabolism, Endocrinology, Insulin, Leptin, Diabetes, Obesity, Sirtuins, 老化、饮食
ORCID: 0000-0002-4764-9558

Alexander Payumo
Assistant Professor of Biological 科学s
Understanding why mammals lose the ability to regenerate their hearts after birth
ORCID: 0000-0002-7733-9622

Melissa Pickett
Assistant Professor of Biological 科学s
Epithelial Cell Polarity, C. elegans, Intestine
ORCID: 0000-0001-8364-4757

Madalyn Radlauer
Associate Professor of Chemistry
Chemistry, Catalysis, Organometallics, Inorganic, Polymers, Environmental and Health 应用程序
ORCID: 0000-0002-3226-5340

Ningkun王
Associate Professor of Chemistry
Allosteric Regulation of Enzymes, SIRT1, Conformational Change, Intrinsically Disordered Proteins, Alzheimer's, Type II Diabetes
ORCID: 0000-0003-3545-5323

Katie Wilkinson
Professor of Biological 科学s
Neurophysiology, Sensory 生理学, Motor Control, Proprioception, Muscle Spindle, 生理学
ORCID: 0000-0002-2692-5533

Potential collaborators and members of the media may contact us at officeofresearch@dienmayhikaru.com.